Outcome of autologous stem cell transplantation in patients with favorable-risk acute myeloid leukemia in first remission - Cancer Cell International

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Outcome of autologous stem cell transplantation in patients with favorable-risk acute myeloid leukemia in first remission - Cancer Cell International
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Autologous hematopoietic stem cell transplantation could be an effective treatment for patients with favorable-risk acute myeloid leukemia in first remission, according to a study published in Cancer Cell International.

/L for three consecutive days and platelet counts ≥ 20 × 10Overall survival was defined from HSCT to death of any cause or last follow-up. Relapse free survival was calculated as the time from transplantation to relapse or the end of follow-up. Relapse was defined as at least 5% leukemia blasts in a BM smear, or extramedullary leukemia.The data were analyzed by the software GraphPad Prism 8 and IBM SPSS statistics 25.

5 additional consolidation courses of chemotherapy including medium-dose cytarabine before transplantation. MRD was negative for all patients before auto-HSCT.All patients had ANC engraftment and the median time of engraftment was 13 days . For platelet, the median time of engraftment was 33 days and 18 patients had platelet engraftment in 100 days post transplantation.The median follow up of the patients was 1362 days .

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