Patients may be at higher risk of overdose when opioidtherapy for pain is discontinued plos plosmedicine
Opioid-related overdose is now a leading cause of accidental death in the United States and Canada. A study published December 1 in the open access journalby Mary Clare Kennedy at University of British Columbia, Kelowna, Canada, and colleagues suggests discontinuing prescribed opioids was associated with increased overdose risk.
In order to better understand associations between discontinuation of prescribed opioid therapy for pain and risk of overdose, researchers conducted a retrospective cohort study of people receiving long-term opioid therapy for pain in British Columbia between October 2014 and June 2018. They analyzed theof 14,037 patients registered with the provincial health insurance client roster in British Columbia who had been on opioid therapy for at least 90 days.
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