New research shows that PET/MRI can help avoid unnecessary biopsies and improve diagnostic accuracy for prostate cancer patients. Applying the PRIMARY scoring system to PET/MRI results can avoid more than 80 percent of unnecessary biopsies, while potentially missing one in eight clinically significant cases.
Apr 13 2024Society of Nuclear Medicine and Molecular Imaging PET/MRI can improve diagnostic accuracy for prostate cancer patients and help avoid unnecessary biopsies , according to new research published in the April issue of The Journal of Nuclear Medicine. By applying the PRIMARY scoring system to PET/MRI results, researchers found that more than 80 percent of unnecessary biopsies could be avoided at the expense of missing one in eight clinically significant prostate cancer cases.
PI-RADS 3 lesions present a dilemma to both urologists and patients because immediate biopsy could be unnecessary; however, a monitoring strategy could lead to some missed diagnoses of clinically significant prostate cancer. Hence, specifically ruling out clinically significant prostate cancer among PI-RADS 3 lesions has significant clinical implications."
In this study, 56 men with PI-RADS 3 lesions underwent 68Ga-PSMA PET/MRI. The five-level PRIMARY system, which is based on a combination of 68Ga-PSMA pattern, localization, and intensity information, was used to report prostate 68Ga-PSMA PET/MRI findings. After imaging, all patients underwent prostate systematic biopsy in combination with targeted biopsy to determine clinically significant prostate cancer.
PET/MRI Prostate Cancer Diagnostic Accuracy Unnecessary Biopsies PRIMARY Scoring System PI-RADS Clinically Significant Cases
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