Positive metabolic effects of gastric bypass disappear quickly -- ScienceDaily

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Positive metabolic effects of gastric bypass disappear quickly -- ScienceDaily
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A new study raises questions about the efficacy of bariatric operations involving gastric bypass. The results show that the biggest metabolic changes happened directly after surgery. Just a year after the operation, the concentration of metabolites and fats had returned to almost the same levels as before the procedure.

A new study from Lund University in Sweden raises questions about the efficacy of bariatric operations involving gastric bypass. The results show that the biggest metabolic changes happened directly after surgery. Just a year after the operation, the concentration of metabolites and fats had returned to almost the same levels as before the procedure.

"Just following up on the weight of people can be a blunt instrument for studying the effects of the procedure. Our study provides a greater understanding of what happens to the metabolism in connection with a gastric bypass operation," says Peter Spégel, associate professor of molecular metabolism at Lund University, who led the study.The study was based on data from 148 people with and without type 2 diabetes who underwent a gastric bypass operation in Sweden.

"We could see the changes while the participants still had a low BMI after the operation. By studying metabolism, we can obtain a clear indication that unhealthy changes are on the way. We hope that the knowledge can be used in follow-up so that preventive measures can be put in place," says Nils Wierup, professor of neuroendocrine cell biology at Lund University and one of the main authors of the article.

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