Understanding what a virus might look like in years to come gives those designing vaccines and therapies a leg up, enabling them to prime more immune systems sooner, so that fewer people die
Like immune responses themselves, however, vaccination generally has to wait for the appearance of the pathogen in question before it can do its stuff. There is therefore a delay between a pathogen’s arrival on the scene and the deployment of a vaccine against it. That delay costs lives.
The starting point for these predictions is the sort of work going on in the laboratory of Jesse Bloom, a virologist at the Fred Hutchinson Cancer Research Centre, in Seattle. Dr Bloom and his colleagues grow variants of coronavirus spike protein in Petri dishes. They then scan through these to discern which mutations have what effects.
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