Stress-related disorders and anxiety are associated with a higher risk of out-of-hospital cardiac arrest, a new case-control study suggests.
There were no significant differences in results when the researchers adjusted for the use of anxiolytics and antidepressants.
Previous research has shown associations of stress-related disorders or anxiety with cardiovascular outcomes, including myocardial infarction, heart failure, and cerebrovascular disease. These disorders might be"biological mediators in the causal pathway of OHCA" and contribute to the increased OHCA rate associated with stress-related disorders and anxiety, the authors suggest.
Each of these factors"may potentially influence cardiac electrophysiology and facilitate ventricular arrhythmias and OHCA." Similarly, other psychiatric disorders, such as depression, can contribute to OHCA risk, but they adjusted for depression in their multivariable analyses.
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