Race-based variations in gut bacteria emerge by 3 months of age -- ScienceDaily

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Race-based variations in gut bacteria emerge by 3 months of age -- ScienceDaily
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Early social and environmental exposures can have large and lasting effects on child development and adult health. One of the systems that is vulnerable to external influence is the gut microbiome. A new study highlights a critical development window during which racial differences in the gut microbiome emerge. The findings are based on analysis of data from 2,756 gut microbiome samples from 729 U.S. children between birth and 12 years of age.

Early social and environmental exposures can have large and lasting effects on child development and adult health. One of the systems in the human body that is vulnerable to external influence is the gut microbiome: the community of bacteria that live in the gastrointestinal tract. Some variations in the human gut microbiome are important because they are linked to the incidence and mortality of various diseases.

Gut microbiome variation associated with race and ethnicity arises after 3 months of age and persists through childhood, according to the new research published Aug. 17 in"The differences that we see are not present at birth, or even shortly after," said Elizabeth Mallott, an assistant professor of biology in Arts & Sciences at Washington University, first author of the new study.

Other studies have shown that race- and ethnicity-associated differences in the gut microbiome reflect differences in environmental and social factors, the authors noted. In the United States, there are clear disparities in health that are tied to socioeconomic differences; culture, diet and access to food; access to health care and education; interactions with the built environment; and environmental pollutants.

The researchers did not attempt to determine which of the race- and ethnicity-related variations were connected with positive or negative impacts on health. But their findings related to the timing of when the variations emerge are important to others who are looking at how the microbiome contributes to adult health and health disparities.

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