Rare, severe liver damage reported in kids in U.S. and Europe

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Rare, severe liver damage reported in kids in U.S. and Europe
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In Alabama, nine otherwise healthy children have developed severe hepatitis. Doctors have yet to pinpoint the cause.

is an inflammation of the liver. The cause is often a virus, but the viruses that commonly cause the illness — hepatitis A, B, C, D and E — have been ruled out in the cases in question, leaving doctors searching for the culprit.

Five of the nine children in Alabama, identified between October 2021 and February, tested positive for adenovirus type 41. Butare respiratory viruses that typically cause the common cold, and are not generally associated with liver injury. In the children in Alabama, symptoms have included diarrhea, nausea and vomiting. Some developed jaundice, and blood tests showed signs of elevated liver enzymes.

"Adenovirus may be the cause for these, but investigators are still learning more, including ruling out the more common causes of hepatitis," CDC spokeswoman Kristen Nordlund said.

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