'Reckless and foolish': Why Russia's vaccine has experts alarmed

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'Reckless and foolish': Why Russia's vaccine has experts alarmed
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Russia's introduction of its vaccine could further complicate the broader discussion around coronavirus vaccines, experts say.

Russia has a coronavirus vaccine. Whether it works is anybody's guess., becoming the first country to do so. The news has been met with strong skepticism, with experts raising concerns that the experimental vaccine has yet to complete clinical trials designed to test its safety and effectiveness.

That rush has already spurred some concern about making sure any vaccines that reach the public are safe and effective, particularly as coronavirus misinformation has run rampant on the internet. Russia's introduction of its vaccine could further complicate the broader discussion around coronavirus vaccines.

Few details have been made available about the Russian vaccine so far, but its approval was based on only the first two phases of clinical trials, which are designed to make early assessments on whether a potential vaccine can induce an immune response, and whether it’s safe to administer in humans. “In Phase 3, you can begin testing on thousands or tens of thousands of people, and you start to build up an understanding of any rare side effects,” said Eleanor Riley, a professor of immunology and infectious diseases at the University of Edinburgh in Scotland. “If you only vaccinate a few hundred people, you won’t see that.”

Riley said that there are instances in which emergency approval of an experimental vaccine may be appropriate, but that the current state of the coronavirus pandemic probably doesn’t apply. In 2018, for instance, an Ebola vaccine was used in the Democratic Republic of the Congo before it had completed clinical trials.

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