Cedars-Sinai investigators are experienced in the use of transcatheter aortic valve replacement (TAVR) with balloon-expandable valves. They now show that redo TAVR procedures are both safe and effective when compared with situations in which patients with similar risk profiles undergo the same procedure for the first time.
To generate their findings, Makkar and team utilized the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry—a national database of all consecutive patients undergoing commercial TAVR in the United States.
Among the 350,591 patients who underwent TAVR between November 2011 and December 2022, 1,320 individuals required redo procedures. The patients who underwent a repeat procedure had a mean age of 78 years old. About 58% were male and 42% female. "Fixing damaged valves is something in which we excel at the Smidt Heart Institute," said Eduardo Marbán, MD, Ph.D., executive director of the Smidt Heart Institute and the Mark Siegel Family Foundation Distinguished Professor."Our finding that TAVR can be redone safely is yet another step in establishing this as the default technology for aortic valve disease."
Interventionalists in the Smidt Heart Institute at Cedars-Sinai have successfully completed more than 6,000 minimally invasive transcatheter aortic valve replacements to date, with more than 650 performed in fiscal year 2022.Outcomes of repeat transcatheter aortic valve replacement with balloon-expandable valves: a registry study,
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