A comprehensive understanding of metabolism enables the prediction of the growth of a crucial environmental microbe. A group led by Professor Ralf Rabus, a microbiologist at the University of Oldenburg, and his Ph.D. student Patrick Becker has made significant advancements in comprehending the cell
A robot punches out pinhead-sized pieces from a gel layer. The narrow blue bands contain proteins from a bacterial culture. Subsequently, the proteins contained in the tiny gel pieces will be sorted in greater detail. Credit: University of Oldenburg/Mohssen Assanimoghaddam
A group led by Professor Ralf Rabus, a microbiologist at the University of Oldenburg, and his Ph.D. student Patrick Becker has made significant advancements in comprehending the cellular processes of a widespread environmental bacterium. The team conducted an extensive analysis of the entire metabolic network of the bacterial strainand utilized the findings to construct a metabolic model that allows them to forecast the growth of these microbes in various environmental conditions.
In particular, substances with a benzene ring composed of six carbon atoms, known as aromatic compounds, can be biodegraded by these microbes – with or without the aid of oxygen. Due to these abilities,plays an important environmental role in the complete degradation of organic compounds in soil and sediments to carbon dioxide – a process which is also useful in biological soil remediation.
Through their meticulous work, the researchers obtained a comprehensive understanding of the metabolic reactions of this bacterial strain. They found that around 200 genes are involved in the degradation processes and determined which enzymes break down the substances added as nutrients and via which intermediates the various nutrients are decomposed.
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