Researchers develop bioengineered cornea that can restore sight to the blind and visually impaired

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Researchers develop bioengineered cornea that can restore sight to the blind and visually impaired
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The affordable implant is an alternative to the transplantation of donated human corneas, which are scarce in countries where the need for them is greatest.

, adjunct associate professor at LiU’s Department of Biomedical Engineering and founder and CEO of the company LinkoCare Life Sciences AB, which manufactures the bioengineered corneas used in the study, told"It has been the longtime goal of many researchers to try solving the problem of shortage in supply of donor corneas for transplantation. And so, we were very interested in addressing it using innovative materials and technologies," says Lagali.

"In many countries, there are large populations affected by this disease. But it isn't detected early and it progresses over time, leading to visual impairment and blindness. At this stage, only a transplant can help. But there's a severe shortage of donor tissue," says Lagali.. But, Rafat states that when a possibility for repairing body tissues and organs arises, it's better to repair than to replace the damaged organ completely.

Lagali interjects: "One of the reasons we chose the material was because the normal human cornea in itself is made of collagen. Also, pig collagen is already being used in cosmetic surgery. So it's not entirely new to the medical field." As Rafat aforementioned, the operations were free from complications. The tissue healed fast, and an eight-week treatment with immunosuppressive eye drops sufficed to prevent implant rejection. The patients were followed for two years, and zero complications were noted during that time.

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