Researchers map lung development after birth into late childhood for the first time ucsandiego
The goal is to build a so-called"reference map" of the human lungs. Such a map would serve as a foundation to understand the cellular differences between healthy and diseased lungs. This work represents a small step toward building a reference for the pediatric population.
"In cases of lung abnormality or disease, we can zoom in and examine what specific types of cells are different from their counterparts in the healthy references and what are the molecular pathways underlying these changes," said Kun Zhang, professor and chair of bioengineering at UC San Diego who is a senior author of the study."Diagnosis and treatment could then be developed based on differences from the reference map.
To construct their map, the researchers analyzed post-mortem human lung tissues that were collected at different time points, starting from day one and up to 9 years after birth. The researchers also collected lung tissue samples from mice at matching time points between one day and nearly one month after birth.
With this analysis, the researchers could start to map developmental pathways for different lung cell types including alveolar epithelial type 1 cells. These cells are vital for the exchange of oxygen and carbon dioxide gases. The researchers gained clues as to how alveolar type 1 cells communicate with other cells such as myofibroblasts, and how this communication could play a role in alveolar cell development.
Deutschland Neuesten Nachrichten, Deutschland Schlagzeilen
Similar News:Sie können auch ähnliche Nachrichten wie diese lesen, die wir aus anderen Nachrichtenquellen gesammelt haben.
I Was Promised That the “Golden Hour” Would Make Me a MomHow an old idea about the time right after birth lives on in American parenting advice.
Weiterlesen »
Kylie Jenner Returned to the Red Carpet in a Latex GownThis marked her first red carpet since giving birth.
Weiterlesen »
How Port Arthur's Oxbow Plant Is Damaging Nearby Communities of Color“We don’t need jobs so bad to where we’re willing to give up the lives of our children and our grandchildren, our mothers and fathers, and our grandparents and ourselves.”
Weiterlesen »
Researchers generate the first complete, gapless sequence of a human genome -- ScienceDailyScientists have published the first complete, gapless sequence of a human genome, two decades after the Human Genome Project produced the first draft human genome sequence. According to researchers, having a complete, gap-free sequence of the roughly 3 billion bases (or 'letters') in our DNA is critical for understanding the full spectrum of human genomic variation and for understanding the genetic contributions to certain diseases.
Weiterlesen »
Ketanji Brown Jackson’s Supreme Court confirmation ‘a sign of hope’ in DallasNot only does Jackson's confirmation mark the first time that a Black woman will on the high court in its 233-year history, and the first time that the...
Weiterlesen »
Google Maps made some key changes. Use them to improve your commute.Depending on where you live and what time you ride, public transportation can be a nightmare. Google Maps may be able to help.
Weiterlesen »