Predictions and picks for the 2022 NFL Week 1 matchup between the San Francisco 49ers and Chicago Bears.
Lorenzo Reyes: 49ers 26, Bears 21
There are so many uncertainties with this game: How will Trey Lance fare as the unquestioned starter? What will Justin Fields and Chicago’s offense look like with Luke Getsy as offensive coordinator? With so much turnover on both sides, I think this game will be closer than many might think, though I still like San Francisco straight up.
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