The technology is promising because it gives scientists new tools to destroy disease-causing agents and clear them from the body.
Novartis's Tallarico tells an illustrative story about why so many are betting on protein degradation. Five years ago, Novartis scientists came up with a list of around 20 targets that they wanted to develop drugs for.
The jury is still out on whether this approach will work, with drugs only beginning to get tested in humans. who is director of the Translational Cancer Research program at the American Cancer Society and has a doctorate in pathology. The cancer nonprofit recently awarded Crews a prestigious ACS Research Professorship.Founded in 2013 to focus on protein degrader development, Connecticut-based biotech Arvinas is the first to test it out in humans, to treat prostate cancer.
But instead, Arvinas sidestepped them, at least in the beginning. Venturing out on into uncharted territory would have been too risky for initial tests of the technology, two top leaders explained to Business Insider.
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