Sex-Specific Protective Effects of Cognitive Reserve on Age-Related Cognitive Decline

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Sex-Specific Protective Effects of Cognitive Reserve on Age-Related Cognitive Decline
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New research aims to understand why women more likely to develop Alzheimer's disease utas_

This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.Females have a higher age-adjusted incidence of Alzheimer disease than males but the reasons for this remain unclear. One proposed contributing factor is that, historically, females had less access to education and, therefore, may accumulate less cognitive reserve.

Baseline cognitive reserve was measured using educational history and IQ, measured by the Wechsler Test of Adult Reading, Full Scale Predicted IQ . Cognitive trajectories for language, executive function, and episodic and working memory over 5 years were extracted from neuropsychological assessments. The adjusted effects of education, estimated IQ, andFive hundred sixty-two individuals were followed up over 5 years with 1,924 assessments and 24,946 cognitive test scores .

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