Silencing tau to treat early Alzheimer’s disease - Nature Medicine

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Silencing tau to treat early Alzheimer’s disease - Nature Medicine
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An ASO therapy reduced tau levels in patients with AlzheimersDisease in a phase 1b trial, but whether this translates to clinical improvement remains to be seen. Read the News and Views from Peter Ljubenkov & Gil Rabinovici RabLab_UCSF UCSFMedicine

P.A.L. receives research search support from the National Institute on Aging of the US National Institutes of Health and from the Alzheimer’s Association Part the Cloud Partnership. He is the FDA investigational new drug sponsor for a clinical trial of a drug supplied by Biohaven. He has served as a clinical site primary investigator for trials sponsored by Woolsey, Alector, Transposon and AbbVie.

He also currently serves as a clinical site sub-investigator for clinical trials sponsored by Lilly, Eisai and Biogen. G.D.R. receives research support from the US National Institutes of Health, the Alzheimer’s Association, the American College of Radiology, the Rainwater Charitable Foundation and the Alliance for Therapies in Neuroscience. He has served as a paid scientific advisor to Alector, Eli Lilly, GE Healthcare, Genentech, Johnson & Johnson Merck, and Roche.

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