There were fewer deaths among people given plasma within three days of diagnosis, but researchers can't say if it was the real reason for improvement.
Mayo Clinic researchers reported a strong hint that blood plasma from COVID-19 survivors helps other patients recover, but it’s not proof and some experts worry if, amid clamor for the treatment, they’ll ever get a clear answer.
There were fewer deaths among people given plasma within three days of diagnosis, and also among those given plasma containing the highest levels of virus-fighting antibodies, Joyner and colleagues reported. “For 102 years we’ve been debating whether or not convalescent plasma works,” said Dr. Mila Ortigoza of New York University, referring to plasma’s use in the 1918 flu pandemic. This time around, “we really need undisputable evidence.”
He’s hopeful the clinical trials will push forward but said the Mayo report is consistent with smaller, earlier plasma studies and “an example of making the best you can of the data that’s available.” The FDA has been closely considering if the evidence is good enough to allow so-called emergency use of convalescent plasma, a step that would make it even harder for more rigorous testing to be completed. FDA didn’t immediately comment Friday.
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