Study of young Marines in basic training could provide coronavirus clues

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Study of young Marines in basic training could provide coronavirus clues
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A Navy research study of 3,500 Marine recruits could help provide answers as to why young adults infected with COVID-19 seem to get mostly mild cases of the disease or may not present any symptoms at all.

The COVID-19 Health Action Response for Marines study -- known by the acronym CHARM -- began in early May and will track up to 3,500 Marine recruits from the moment they arrive at the location where they will quarantine for 14 days before they head to basic training at Marine Corps Recruit Depot Parris Island in South Carolina.

A poolee is tested for COVID-19 at The Citadel, a public military college temporarily utilized to stage poolees for a 14-day observation period in Charleston, S.C., May 5, 2020.Upon arrival each volunteer gets a nasal, saliva and blood test to determine if they have the novel coronavirus, followed by a similar round of tests the following week and four more tests every two weeks.

As of last week slightly more than 2,000 Marines had been tested as part of the study, with the goal of ultimately testing 3,500. The regular blood tests measure the various components of the human immune system including the cells that make antibodies, the cytokine markers that detect a virus in the body and the T-cells that help coordinate the immunological response to the disease.

"Well, the factory needs to receive an order from somewhere, telling it 'Hey, you need to make more of these things,'" said Letizia.

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