Study suggests anxiety increases the risk of subsequent cognitive progression in non-dementia elderly eBioMedicine anxiety dementia disease health
By Hugo Francisco de SouzaJul 14 2023Reviewed by Benedette Cuffari, M.Sc. In a recent study published in eBioMedicine, researchers investigate the effects of anxiety on cognitive degeneration in non-dementia elderly. To this end, a multi-omics approach was used to elucidate the biological mechanisms contributing to cognitive impairment.
AD is identified by hyperphosphorylated tau protein upregulation and increased extracellular amyloid beta deposition. To date, there is no cure for AD. About the study In the present study, researchers selected individuals from the Chinese Longitudinal Healthy Longevity Survey , Alzheimer's Disease Neuroimaging Initiative , and Shanghai Mental Health Center cohorts as participants in the study.
For cognitive validation, 732 anxious and 1,464 normal elderly were administered the Chinese Mini-Mental State Examination . Similar to the ADNI study, follow-up visits with were conducted for up to 204 months.
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