Early results from 20 people with opioid use disorder raise hopes that popular weight-loss drugs like Wegovy can tackle opioid addiction, too.
A weight-loss drug used to treat obesity and diabetes has shown promise to treat another disorder: opioid addiction.
“For them to have any time when they might be free of that craving seems to be very hopeful,” Patricia “Sue” Grigson, a behavioral neuroscientist at Penn State College of Medicine in Hershey said at the conference. The vast majority of drug overdose deaths in the United States areThe drug, called liraglutide, mimics a hormone called GLP-1 that the body releases after people eat.
At higher doses of liraglutide, patients dropped out of the trial largely due to gastrointestinal symptoms including nausea, a known side effect of these drugs. Still, the treatment began reducing opioid cravings at the lowest dose, Grigson said, and desire for opioids was reduced by 30 percent overall.
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Novo Nordisk settles two lawsuits over copycat versions of Ozempic and WegovyBerkeley Lovelace Jr. is a health and medical reporter for NBC News. He covers the Food and Drug Administration, with a special focus on Covid vaccines, prescription drug pricing and health care. He previously covered the biotech and pharmaceutical industry with CNBC.
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