The disease burden and clinical severity of the SARS-CoV-2 Omicron BA.2 sublineage outbreak in Shanghai medrxivpreprint IUSPH Omicron SARSCoV2 COVID19 coronavirus covid disease
By Tarun Sai LomteJul 14 2022Reviewed by Danielle Ellis, B.Sc. In a recent study posted to medRxiv*, researchers estimated the severity and burden of coronavirus disease 2019 in a recent outbreak in Shanghai, China.
Nonetheless, these measures were inadequate to contain community transmission. On April 1, 2022, a lockdown was enforced that ended on June 1, 2022. Estimating the severity and burden of the disease is crucial to strategize appropriate interventions and plan for adequate health care requirements. Cases were classified as severe if they developed: low oxygen saturation, breathing difficulty, low arterial oxygen partial pressure to fractional inspired oxygen ratio, or progressive symptoms with imaging analysis revealing progressive lesions within 24-to-48 hours. Patients were deemed critical if admitted to the intensive care unit . PCR-positive individuals who showed no clinically identifiable signs/symptoms or pneumonia were categorized as asymptomatic.
Related StoriesPasym was estimated as the ratio of the number of asymptomatic cases to the total number of infections. ISR was defined as the ratio of the number of severe/critical cases to total PCR-positive cases. sCSR was the ratio of severe/critical cases to the number of symptomatic cases. IFR was the ratio between the number of deaths and total infections. sCFR was the number of deaths to the total number of symptomatic patients.
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