The safety of mesenchymal stem cell therapy for treating severe COVID-19 SciReports stemcell therapy stemcelltherapy therapy COVID19 SARSCoV2
By Dr. Sanchari Sinha Dutta, Ph.D.Aug 7 2023Reviewed by Benedette Cuffari, M.Sc. In a recent study published in Scientific Reports, researchers discuss the results of a multicentric, randomized, placebo-controlled trial to determine the safety and efficacy of normoxic-allogenic umbilical cord mesenchymal stem cells in treating severe coronavirus disease 2019 patients.
Hyper-inflammation and the ‘cytokine storm’ are considered key indicators of severe COVID-19, which is associated with significant morbidity and mortality. Cytokine release syndrome caused by the cytokine storm acts together with chemokine release to induce multiorgan failure in severe COVID-19 patients.
In this randomized, placebo-controlled trial, scientists investigate the safety and therapeutic efficacy of normoxic-allogenic umbilical cord MSCs as an adjunctive treatment in severe COVID-19 patients. The primary aim of the trial was to assess the effect of intervention on the duration of hospital stay. The researchers also assessed radiographical progression, respiratory and oxygenation parameters, inflammatory parameters, as well as the safety profile of this treatment.
An improvement in dyspnea, which refers to difficulty breathing, was observed in both the groups at 15 and 22 days after treatment initiation. A six-minute walk test performed by the patients from both groups showed comparable scores post-treatment. A total of 14 patients, seven from each group, died during the treatment period. In both groups, no severe adverse effects were observed until day 91.
Deutschland Neuesten Nachrichten, Deutschland Schlagzeilen
Similar News:Sie können auch ähnliche Nachrichten wie diese lesen, die wir aus anderen Nachrichtenquellen gesammelt haben.
The Irish Light: Woman abused by paper which falsely said vaccine killed her sonPromoting a Covid conspiracy theory, the Irish Light's editor accuses the mum of 'massive fraud'.
Weiterlesen »
Memorial garden to Covid victims and organ donors at Royal Preston HospitalThey will not be forgotten. LancsHospitals opens memorial gardens at Royal Preston and Chorley hospitals to remember those lost to coronavirus and also those who died and donated organs ❤️
Weiterlesen »
New Covid variant Eris found spreading rapidly in UK as cases spike across agesEris is the second most prevalent strain in the UK a month after it was raised a concern by UK health officials.
Weiterlesen »
Top doctor warns of 'silent' pandemic that could be 'worse than Covid'A doctor has warned that a 'silent' pandemic in the UK could end up being worse than the Coronavirus
Weiterlesen »
Virgin Atlantic pilots consider strike over fatigueMembers of the Balpa union have 'serious concerns' over schedules put in place during Covid.
Weiterlesen »