A handful of the dozens of experimental Covid-19 vaccines in human testing have reached the last and biggest hurdle — looking for the needed proof that they really work
The Cambridge, England-based company said the study will involve up to 30,000 adults from various racial, ethnic and geographic groups.Two other vaccine candidates began final testing this summer in tens of thousands of people in the U.S. One was created by the National Institutes of Health and manufactured by Moderna Inc., and the other developed by Pfizer Inc. and Germany’s BioNTech.
AstraZeneca said development of the vaccine known as AZD1222 is moving ahead globally with late-stage trials in the U.K., Brazil and South Africa. Further trials are planned in Japan and Russia. The potential vaccine was invented by the University of Oxford and an associated company, Vaccitech. They’re made in a wide variety of ways, each with pros and cons. One problem: Most of the leading candidates are being tested with two doses, which lengthens the time required to get an answer — and, if one works, to fully vaccinate people.
These mRNA vaccines are easier and faster to make than traditional vaccines, but it’s a new and unproven technology.Britain’s Oxford University and AstraZeneca are making what scientists call a “viral vector” vaccine but a good analogy is the Trojan horse. The shots are made with a harmless virus — a cold virus that normally infects chimpanzees — that carries the spike protein’s genetic material into the body.
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Third virus vaccine reaches major hurdle: final US testingA handful of the dozens of experimental COVID-19 vaccines in human testing have reached the last and biggest hurdle — looking for the needed proof that they really work. AstraZeneca announced Monday its vaccine candidate has entered the final testing stage in the U.S. The Cambridge, England-based company
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AstraZeneca's coronavirus vaccine becomes third to begin Phase three trials in the United StatesBritish drugmaker AstraZeneca says it has started Phase 3 trials of its coronavirus vaccine candidate in the United States. The vaccine, AZD 1222, is the third to enter large-scale trials in the United States, after vaccines made by Moderna and Pfizer/BioNTech.
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