Thyroid Dysfunction May Linger a Year After Severe COVID-19

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Thyroid Dysfunction May Linger a Year After Severe COVID-19
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Patients hospitalized with severe COVID-19 and no prior history of thyroid dysfunction show signs of thyroiditis that, although asymptomatic, continue to persist for up to a year after infection, according to recent research. ATA2022

that a painless, atypical thyroiditis occurs with nonthyroidal illness syndrome among patients hospitalized with severe COVID-19. The atypical thyroiditis was slightly more common in men and was associated with lymphopenia.

Importantly, 60% of those patients with the areas of thyroiditis had low TSH levels, while 25% had normal TSH levels . In terms of thyroid uptake, at 3 months, 14 of 17 patients had diffused or focal areas of a reduction of uptake. After 6 months, there was a recovery, with a median of 28% of thyroid uptake recovered, however, 67% of patients still had some focal or diffused reduction in thyroid uptake.

Additional assessments at 8 months after infection showed those tissue resident memory T cells continued to be present on imaging.

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