President Donald Trump's continued embrace of hydroxychloroquine, an anti-malaria drug with unproven efficacy against the novel coronavirus, directly contradicts guidance from the nation's top public health agencies and officials. Approved decades ago to prevent and treat malaria, the prescription
President Donald Trump's continued embrace of hydroxychloroquine, an anti-malaria drug with unproven efficacy against the novel coronavirus, directly contradicts guidance from the nation's top public health agencies and officials.
March 19: Trump declares drug a 'game changer'As parts of the country start shutting down in an effort to curb virus spread, Trump announces the FDA will fast-track approval of unproven coronavirus treatments, including chloroquine and hydroxychloroquine. "But I'm a big fan, and we'll see what happens," Trump steps forward to add."I feel good about it. That's all it is, just a feeling, you know."
The publisher issues a notice two weeks later saying the study"does not meet the Society's expected standard, especially relating to the lack of better explanations of the inclusion criteria and the triage of patients to ensure patient safety." March 28: FDA approves emergency use of hydroxychloroquineThe FDA issues an emergency use authorization to allow"hydroxychloroquine sulfate and chloroquine phosphate products" donated to the Strategic National Stockpile to be distributed to hospitalized patients with COVID-19.
"We don't have time to go and say, 'Gee, let's take a couple of years and test it out. And let's go and test with the test tubes and the laboratories,'" Trump says at a task force briefing.
"We have tremendous endorsements, but if it was somebody else other than President Trump that put it forward, if some other person put it forward that said, 'Oh, let's go with it.' You know, what do you have to lose?" Trump says. "Hydroxychloroquine and chloroquine can cause abnormal heart rhythms such as QT interval prolongation and ventricular tachycardia. These risks may increase when these medicines are combined with other medicines known to prolong the QT interval, including azithromycin," the FDA says.
When patients received a combination treatment of hydroxychloroquine and an antibiotic, the combo Trump promoted, they were more than twice as likely to experience cardiac arrest as those who took neither drug. "Additionally, in light of ongoing serious cardiac adverse events and other potential serious side effects, the known and potential benefits of chloroquine and hydroxychloroquine no longer outweigh the known and potential risks for the authorized use," it continues.
July 28: Trump tweets video on hydroxychloroquine flagged by Twitter as misleadingTwitter flags and later takes down a video retweeted by Trump and directly shared by Donald Trump Jr. that featured a woman identifying as a doctor promoting hydroxychloroquine as a COVID-19"cure," for violating the company's policies on misinformation related to the pandemic.
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