Researchers develop bloodtest for anxiety iumedschool MolPsychiatry
For the biomarkers identified by us, combining all the available evidence from this current work into a CFE score, brings to the fore biomarkers that have clinical utility for objective assessment and risk prediction for anxiety disorders . These biomarkers should be tested individually as well as tested as polygenic panels of biomarkers in future clinical studies and practical clinical applications in the field.
. This subject was previously described by us in a suicidality biomarker study, as high risk for suicide, and died by suicide a year after completing our study. No information was provided to the patient’s clinicians by us at that time due to anonymity and privacy rules in research studies. The raw expression values of the 19 biomarkers for the high and low anxiety groups were Z-scored by gender and diagnosis.
In regards to how our biomarker discoveries might be applied in clinical laboratory settings, we suggest that panels of top biomarkers, such as BioM-19, be used . In practice, every new patient tested would be normalized against the database of similar patients already tested, and compared to them for ranking and risk prediction purposes, regardless if a platform like microarrays, RNA sequencing, or a more targeted one like PCR is used in the end clinically.
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