Trends in the prevalence of hospital-associated infections caused by high-priority pathogens

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Trends in the prevalence of hospital-associated infections caused by high-priority pathogens
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Trends in the prevalence of hospital-associated infections caused by high-priority pathogens PLOSMedicine HopkinsMedicine infection pathogen bacteria disease

By Bhavana KunkalikarJun 19 2023Reviewed by Danielle Ellis, B.Sc. In a recent study published in PLOS Medicine, researchers explored the prevalence of antibiotic-resistant hospital-associated infections worldwide.

Prevalences of antibiotic resistance were reported for 122 antimicrobials. Thirteen categories were identified, including tetracyclines, sulfonamides, penicillins, monobactams, macrolides, quinolones, aminoglycosides, amphenicols, cephalosporins, polymyxins, carbapenems, glycopeptides, and a miscellaneous group referred to as "others."

Results A total of 474 publications from 99 countries reported on antibiotic resistance proportions for hospital-associated infections. Approximately 15,723 resistance proportions were obtained from six groups of pathogens, including 4,014 of E. coli, 3,524 of Klebsiella spp., 2,979 of Staphylococcus spp., 2,296 of Acinetobacter spp., 1,791of Pseudomonas spp., and 1,119 of Enterobacter spp.

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