TPOXX, as the drug is marketed, is an antiviral currently approved for treatment of human smallpox in adults and children caused by the variola virus.
The study is a randomized, placebo-controlled, double-blind trial, funded by the National Institute of Allergy and Infectious Diseases and led by the AIDS Clinical Trial Group. The AntiViral Research Center at UCSD School of Medicine is part of the group.
"People living in the San Diego region who have confirmed or probable Mpox have the opportunity to make a huge contribution by participating in this study." The new trial, with more than 60 sites, will enroll more than 500 adults with monkeypox virus infections. The trial will include people with severe disease and those at high risk of severe disease, including pregnant and breastfeeding persons, children and individuals with underlying immune deficiency and active inflammatory skin conditions who will receive open-label tecovirimat, a statement from the university reads.
is unknown. The virus belongs to the same family of viruses as variola virus. MPOX symptoms are similar to smallpox symptoms, but milder, and MPOX is rarely fatal. MPOX is not related to chickenpox.
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