Autism spectrum disorder is a much more prevalent co-occurring condition in individuals with fragile X than previously realized, according to new research. It is also underdiagnosed in community settings.
, principal investigator Jessica Klusek and her team conducted comprehensive, best-practice clinical autism diagnostic assessments in with fragile X syndrome . They found that, although 75 percent of participants met criteria for autism through the research protocol, only 31 percent had been identified as having autism in the community.
"Individuals with both fragile X syndrome and autism spectrum disorder are at risk for poorer education, medical, employment and independent living outcomes, sois essential to providing access to services that improve their success and quality of life in these areas." One in every 36 children has been identified with autism spectrum disorder, according to the Centers for Disease Control and Prevention, but this condition is even more prevalent in children with certain, such as fragile X syndrome which affects one in 7,000 boys and one in 11,000 girls. Klusek's research shows that about 75 percent of boys with fragile X meet criteria for co-occurring autism.
However, without a genetic or other lab test for autism, clinical and educational providers rely on their own assessments to identify the disorder, which can pose challenges. The features of fragile X syndrome and autism spectrum disorder are often similar, leading to misattribution of observed symptoms by parents, teachers and clinicians.
In Klusek's study, the researchers found that of the participants who met the clinical standards for autism spectrum disorder, 60 percent had not been previously diagnosed within their communities. Forty percent of the participants had never been evaluated for autism at all.
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