Unlocking the gut clock: How circadian rhythms and gut microbiota team up to impact human health CircadianRhythm Depression Diet Food Metabolism Metabolites Nutrition Chronotype microbiome Els_Nutrition UNI_FIRENZE
By Dr. Sanchari Sinha Dutta, Ph.D.May 15 2023 In a review article published in the journal Nutrition, Metabolism, and Cardiovascular Diseases, scientists have provided an overview of recent studies investigating the association between circadian rhythms, gut microbiota, and diet and the collective impact of this association on general health.
A considerable proportion of total gut microbiota composition fluctuates rhythmically throughout the day. Moreover, the gut microbiota itself synchronizes the circadian biological clocks of the host through different signaling pathways. These observations indicate that there might be crosstalk between host circadian rhythms and gut microbiota and that dietary patterns and timings might play a crucial role in this interplay.
Related StoriesTime-restricted feeding refers to the consumption of a desired amount of food during a specific time period. This particular dietary pattern has been found to modulate gut microbiota composition, such as the induction of beneficial bacterial communities and the reduction of harmful bacterial communities. Such restriction in food access time is believed to mimic natural eating patterns based on circadian rhythms.
The Mediterranean diet is considered one of the best dietary patterns with many health benefits. This diet is known to reduce the risk of cardiovascular and metabolic diseases and all-cause morbidity and mortality. Studies have shown that the morning chronotype is associated with higher adherence to the Mediterranean diet and better body weight management.
There is evidence showing that evening chronotype is associated with altered cardiometabolic profiles. A significantly altered lipid and glucose metabolism and gut microbiota rhythmicity has been observed among evening-time eaters.
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