Two new studies involving monkeys suggest COVID-19 vaccine candidates can provide disease protection after a single injection — but it will take large-scale human trials to know for sure if they work.
. It uses a harmless virus to transfer genetic material from the coronavirus into the person being vaccinated. It's an approach the company has been using for years.
"We have now vaccinated 80,000 people with the vector in different diseases," said Paul Stoffels, chief scientific officer of Johnson & Johnson. And it's known to be safe., researchers at the National Institute of Allergy and Infectious Diseases tested another viral vector vaccine, this one developed by the University of Oxford. Some animals receive a single vaccination; some received two.
None of the vaccinated monkeys developed disease, but all of them still showed signs of active infection in their upper airways. As of July 1, about 8,000 human volunteers had participated in a study of the Oxford vaccine. If it is shown to prevent disease in humans, that of course would be a good thing. But if it doesn't prevent infection of the upper airway, it means a vaccinated person could still spread the disease.
He said only when the human trials have results will we know for sure if any of the vaccines being tested will actually work.
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