Vaccine Effectiveness Against Infection May Wane, CDC Studies Find

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Vaccine Effectiveness Against Infection May Wane, CDC Studies Find
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The Centers for Disease Control and Prevention released three studies Wednesday that federal officials said provided evidence that booster shots of the Pfizer-BioNTech and Moderna coronavirus vaccines would be needed by all Americans in the coming months.

Antonia Aponte, 74, receives a dose of the Moderna coronavirus vaccine at The Castle Hill Community Center in the Bronx on Feb. 4, 2021.

The decline in effectiveness against infection may result from waning vaccine immunity, a lapse in precautions like wearing masks or the rise of the highly contagious delta variant, experts said — or a combination of all three. “Feeling sick like a dog and laid up in bed, but not in the hospital with severe COVID, is not a good enough reason” for a campaign of booster shots, Gounder said. “We’ll be better protected by vaccinating the unvaccinated here and around the world.”

“Those numbers are actually very good,” Murray said. “The only group that these data would suggest boosters for, to me, is the immunocompromised.” “This is part of why I think the administration’s focus on vaccines is so damaging to morale,” she added. “We probably won’t be going back to normal anytime soon.”

Nursing homes were required to report the number of immunized residents only after June 6, which “makes comparisons over time very challenging,” Murray said. “It’s fully possible that the vaccine effectiveness reported here hasn’t actually declined over time.” During those weeks, New York recorded 9,675 breakthrough infections — roughly 20% of total cases in the state — and 1,271 hospitalizations in vaccinated people, which accounted for 15% of all COVID-19 hospitalizations.

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