A chemical analysis of the letters of the legendary historical figure reputed to have inspired fictional vampire Dracula has revealed Vlad Drăculea (aka Vlad the Impaler) may have cried tears of blood.
and water-repelling resins, has been used to promising effect with ancient fabrics and papers.
When applied to any type of surface, this film is able to extract proteins and molecules without damaging the surface.The team used these films on three of the Vlad Drăculea letters, one dated 1457, the other two 1475, and used mass spectrometry to analyze the results. They found thousands of peptides and proteins. They focused on signals of human biology; and, because many people have handled the letters over the centuries, only the human material with the most advanced degradation.
that results in chronic lung and sinus infections. They also found peptides belonging to proteins associated with inflammatory processes. Put together, this suggests a skin or respiratory disorder – or perhaps both. They also found peptides associated with proteins of the retina and tears, and also blood proteins. There were reports, the researchers assert, that Vlad Drăculea cried bloody tears; indeed, the concept has been popular inof Dracula. Although far from a smoking gun, this suggests that there may be some truth to that rumor.
"Altogether, proteomic data here reported, although cannot be considered exhaustive alone, might indicate that, according to some stories, he probably suffered, at least in the last years of his life, from a pathological condition called hemolacria, that is, he could shed tears admixed with blood,"
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