After nearly two months of lab studies and real-world observations, experts have a much clearer picture of what Omicron is — and isn’t — capable of
that fewer than 15 percent of early Omicron patients in the Houston Methodist health care system had to be hospitalized, compared with 43 percent of the system’s early Delta patients and 55 percent of its early Alpha patients.Burn-Murdoch, “has significantly weakened with Omicron.”A woman is tested at a pop-up site in New York City's Times Square.
In lay terms, that simply means the new variant doesn’t take hold or grow in the lungs as easily as older variants, possibly because its many mutations make it harder for a special protein on the surface of lung cells to latch onto it. One study found that Omicron levels in the lungs were one-tenth or less the level of other variants.
This has led some scientists, such as Ravindra Gupta, a virologist at the University of Cambridge, to speculate that Omicron has evolved into an upper-airway specialist,“It’s all about what happens in the upper airway for it to transmit, right?” Gupta recently. “It’s not really what happens down below in the lungs, where the severe disease stuff happens. So you can understand why the virus has evolved in this way.
A third booster dose helps here because it almost immediately increases neutralizing antibodies 20- to 40-fold; reports from both South Africa and the U.K. suggest that boosters are about 70 percent effective against symptomatic infection, at least at first.already administering fourth doses to seniors, health workers and immunocompromised patientsWhat is much less likely to fade is the strong protection the existing vaccines provide against severe disease.
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