Experts say the blister-like mark is actually a good sign.
What’s more, a wheal is not specific to the Jynneos vaccine. “Any medication given intradermally will produce a wheal; this includes medications such as the [What does a wheal feel like and how long does it typically last?
In some cases, the wheal may feel slightly tender or itchy, and it may become red on some people, depending on their skin tone, Dr. Rivard says. Fortunately, this should resolve quickly in most cases, clearing up in about 24 to 72 hours, she says. During this time, you should avoid rubbing the area or putting any pressure on it, which your provider may cover with a bandage after the vaccine is administered.
For others, the wheal may last longer. “In rare instances, the redness or swelling at the site of administration may last six to eight weeks and may resolve slower,” Dr. Rivard says. “In very rare circumstances, there can be long-term skin discoloration, nodules, or scarring at the site.”The second dose of the Jynneos vaccine is given 28 days after the first, regardless of whether the vaccine is administered as an intradermal injection or subcutaneously, per the.
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