'Changes in brain chemistry occur during certain life transitions that can predispose someone to developing a new psychotic disorder.' And for women, that can mean menopause. Here's why.
and adulthood is a typical time that young men first develop schizophrenia. Even though women’s brains develop faster than men's, their risk window for a first episode of schizophrenia is older than men's, suggesting that women, for some reason, have protection from developing chronic psychotic disorders.
If women do develop schizophrenia, they tend to have a milder course than men and respond to lower amounts of, though this can partly be explained by average body size and how women metabolize medications. Scientists point to estrogen as the obvious protective factor. This hypothesis would seem to be supported by the fact that times when women have relatively lower estrogen levels , they are at higher risk for more symptoms of mental illness. Also, unlike men, women have a second risk period during life for developing schizophrenia at or around menopause, when estrogen levels drop for good.
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