Conditions that affect women more than men garner less funding. But boosting investment could reap big rewards.
Each of these circles represents a disease, with circle area representing disease burden — a measure of how much death and disability it causes.For orange circles, at least 60% of people with the disease are women.Light blue and light orange circles represent diseases in which men or women, respectively, are slightly dominant, from 55% to 60%.
Migraine, headaches, endometriosis and anxiety disorders, for example, which disproportionately affect women, all attract much less funding in proportion to the burden they exert on the US population than do other conditions. The 2021 analysis “demonstrates that the funding of research for women is not aligned with burdens of disease”, says Sarah Temkin, associate director for clinical research at the NIH Office of Research on Women’s Health in Bethesda, Maryland.
. But even so, women are not necessarily included in proportions that match the prevalence or burden of disease. For instance women comprised 42.9% of participants in oncology clinical trials between 2000 and 2020, but experienced 46.5% of the burden4. In neurology and immunology, too, women were under-represented.Source: Ref. 4
Across the four diseases, the NIH budget for women-focused research was $350 million. The study modelled what might happen if that doubled, and assumed that this increase would deliver a slight improvement to health in terms of life expectancy, disease progression and quality of life.
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