A recent study compared infant gut microbiome composition before and during the COVID-19 pandemic.
By Tarun Sai LomteAug 21 2023Reviewed by Sophia Coveney A recent study published in Scientific Reports compared infant gut microbiome composition before and during the coronavirus disease 2019 pandemic.
About the study In the present study, researchers compared infant gut microbiomes before and after the start of the COVID-19 pandemic. Neonates born after or at 36 gestational weeks in New York City with no developmental or neurological delays were included. Data were first collected from April 2018 to December 2019, when infants were aged three months.
The team performed 16s rRNA sequencing and generated alpha diversity estimates, focusing on the Shannon and Chao1 indices. Chi-squared and t-tests were used to compare the environmental and demographic characteristics of the pre-pandemic and pandemic groups. Measures with significant differences were used in subsequent analyses.
Related StoriesThere were no significant differences in socioeconomic status, lifestyle factors, racial demographics, material hardship, and mental health of caregivers between pre-pandemic and pandemic groups. However, the average daily fat intake increased significantly after the pandemic. As such, beta diversity was tested using the unweighted UniFrac distance. The researchers noted significant differences in gut microbial richness between pandemic and pre-pandemic samples. Further, the relative abundance of taxa from the Pasteurellaceae family and Haemophilus genus was lower in infants during the pandemic than before.
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