COVID-19 shots for U.S. infants, toddlers and preschoolers moved a step closer Wednesday.
The Food and Drug Administration's vaccine advisers gave a thumbs-up to vaccines from Moderna and Pfizer for the littlest kids.
"Risks from vaccination are very low, but so are risks from COVID-19 for the youngest kids," said Dr. Cody Meissner of Tufts University. "You can’t compare the vaccines directly," said Dr. Jesse Goodman of Georgetown University, a former FDA vaccine chief. Moderna’s shots are one-quarter the dose of the company’s adult shots. Two doses appeared strong enough to prevent severe illness but only about 40% to 50% effective at preventing milder infections. Moderna has added a booster to its study and expects to eventually offer one.
Several advisers, noting that protection is low after two Pfizer doses, worried that some parents might end up skipping the third shot, or mistakenly thinking their kids are better protected between shots, leaving them vulnerable. Moderna said in April that it is also seeking regulatory approval outside the U.S. for its little kid shots. According to the World Health Organization, 12 other countries already vaccinate kids under 5, with other brands.
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