Hydroxychloroquine fails to prevent coronavirus: study in NEJM - Business Insider

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Hydroxychloroquine fails to prevent coronavirus: study in NEJM - Business Insider
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The first high-quality study of malaria pill hydroxychloroquine just found it doesn't help prevent coronavirus infections

The malaria drug hydroxychloroquine doesn't help prevent coronavirus infections in people who were recently exposed to the virus, study results set to be published Wednesday show.

. Infection rates were about the same for people taking hydroxychloroquine or a placebo. The study is set to be published Wednesday in The New England Journal of Medicine. In an interview with Business Insider, Boulware said hydroxychloroquine should not be used as a post-exposure preventive therapy, based on the results. "This trial is fairly conclusive that there is not a benefit for post-exposure prophylaxis," Boulware said. "If you're the general public, if you're the president or anyone, and you're exposed to somebody with known COVID, taking this is not going to reduce your risk of developing infection.

Volunteers and the researchers didn't know who got the drug and who got a placebo. The study randomly assigned 821 people to either a five-day regimen of hydroxychloroquine or placebo. The politicization led many people to make up their minds on whether the drug works, despite a lack of quality data, he said. Boulware said hydroxychloroquine's supporters felt his study was unethical because it used a placebo group. Since they believed the pills were an effective treatment, they felt it would be unethical to withhold them from some people.

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