Is there an association between COVID-19 vaccination and changes in ovarian reserve? bcmhouston JAMANetworkOpen txfertility COVID19 coronavirus covid ovary ovarian womenshealth health vaccine vaccination
By Bhavana KunkalikarJun 22 2023Reviewed by Danielle Ellis, B.Sc. In a recent study published in the JAMA Network Open, researchers explored the difference in female ovarian reserve before and after receiving the coronavirus disease 2019 vaccine.
The study aimed to investigate the correlation between COVID-19 vaccination and AFC and AMH levels in women undergoing fertility treatment, considering the alterations in AMH assays and the requirement for cross-referencing other biomarkers. The study's main focus was measuring ovarian reserve, which was determined by AFC or AMH level. The study utilized heteroskedastic linear regression to adjust heteroskedastic data. The outcome variables included age, body mass index , type of AMH assay, hemoglobin A1c level, and vaccination status. The study's dependent variable was either the AFC or AMH level.
Related StoriesThe study found a notable contrast in vaccinated patients based on the type of AMH assay used. Specifically, there were 259 patients in the prevaccination group compared to 137 patients in the postvaccination group who were tested using the current assay. Age and AMH platform were found to be associated with AMH value, while vaccination status exhibited no such association in a linear regression model.
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