Low-fat vegan diet outperforms Mediterranean diet in reducing AGEs and achieving weight loss

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Low-fat vegan diet outperforms Mediterranean diet in reducing AGEs and achieving weight loss
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Eating a low-fat vegan diet reduces harmful inflammatory dietary compounds called advanced glycation end-products (AGEs) by 73%, compared to no reduction on a Mediterranean diet, according to new research by the Physicians Committee for Responsible Medicine published in Frontiers in Nutrition.

Physicians Committee for Responsible Medicine Aug 9 2024 Eating a low-fat vegan diet reduces harmful inflammatory dietary compounds called advanced glycation end-products by 73%, compared to no reduction on a Mediterranean diet, according to new research by the Physicians Committee for Responsible Medicine published in Frontiers in Nutrition . The decrease in AGEs on the vegan diet was associated with an average weight loss of 13 pounds, compared with no change on the Mediterranean diet.

The study helps bust the myth that a Mediterranean diet is best for weight loss. Choosing a low-fat vegan diet that avoids the dairy and oil so common in the Mediterranean diet helps reduce intake of harmful advanced glycation end-products leading to significant weight loss." AGEs may be ingested through the diet, and animal products are generally higher in AGEs than plant foods. Cooking with high heat under dry conditions, such as grilling, leads to significant formation of AGEs, especially in animal-derived foods, which are also rich in fats. High amounts of AGEs circulating in the body can contribute to insulin resistance, which can lead to weight gain.

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