Novel skin patch could help treat peanut allergies in toddlers

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Novel skin patch could help treat peanut allergies in toddlers
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A daily-use patch administers immunotherapy through the skin.

They were all tested for peanut sensitivity to determine their tolerance to various doses of peanut protein.After a year of treatment, the results revealed that approximately two-thirds of the toddlers could safely consume some peanuts. It was especially beneficial for toddlers who couldn't tolerate even a trace of peanuts but were able to eat a few after applying this patch.

Nearly two percent of children in the U.S. are allergic to peanut-containing foods. Even minor exposure can cause severe reactions such as inflammation, hives, or wheezing in some. According to experts, some people outgrow their peanut allergy as they get older. Nevertheless, they still have to avoid peanuts for life.

“If approved, the Viaskin Peanut patch has the potential to give new hope to toddlers and their families who currently have no approved treatment options and must instead rely on avoidance, which can severely impact the quality of life. The EPITOPE data are a meaningful advancement in potentially offering the first-ever FDA-approved treatment option for peanut-allergic toddlers,” said Matthew Greenhawt, M.D.

We conducted this phase 3, multicenter, double-blind, randomized, placebo-controlled trial involving children 1 to 3 years of age with peanut allergy confirmed by a double-blind, placebo-controlled food challenge. Patients who had an eliciting dose of 300 mg or less of peanut protein were assigned in a 2:1 ratio to receive epicutaneous immunotherapy delivered by means of a peanut patch or to receive placebo administered daily for 12 months.

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