A single-patient study on a man with Parkinson's disease may have pointed to a new kind of therapy treatment for the millions with the neurodegenerative disease, researchers said
- Skin cells reprogrammed to produce the neurotransmitter dopamine and inserted deep into the brain of a 69-year-old man with Parkinson’s disease have allowed him to tie his shoes again and resume swimming and biking, researchers reported in The New England Journal of Medicine on Wednesday.
Parkinson’s, a progressive disease that affects millions of people worldwide, produces tremors, stiffness, and problems walking and speaking as the dopamine-producing cells in the brain degenerate. There have been no side effects from the treatment, and by retraining the patient’s own cells, “we solved the rejection problem,” lead researcher Dr. Kwang-Soo Kim, who directs the Molecular Neurobiology Laboratory at McLean Hospital in Belmont, Mass., told Reuters.
The patient, identified by statnews.com as George “Doc” Lopez, a physician, businessman and inventor, provided $2 million to help speed the early research. Additional funding came from the U.S. National Institutes of Health.
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