Researchers from DZNE and Otto von Guericke University Magdeburg have identified individuals with increased risk for dementia using mobility data, recorded during a smartphone-based wayfinding task on the university campus.
DZNE - German Center for Neurodegenerative Diseases Oct 3 2024 The findings, reported in the journal PLOS Digital Health, show the potential of smartphone data, collected in conditions close to everyday life, for the early detection and monitoring of Alzheimer's disease. The study included 72 adults; about a third of them with subjective cognitive decline , a condition that is a known risk factor for dementia.
Currently, Alzheimer's is often treated too late to ensure effective therapy. Even the new antibody drugs that are being much discussed at the moment only work if they are given at an early stage. Thus, we need to be able to diagnose the disease earlier, when symptoms are still mild. This requires advances in diagnostics." With colleagues, she now tested a novel approach to assessing problems in spatial navigation, as one of the first potential symptoms of Alzheimer's disease.
"Scavenger hunt" on the campus In total, 72 women and men between the ages of their mid-twenties and mid-sixties participated in the study. Of the 48 older individuals, 23 were diagnosed as SCD patients. People with this condition perceive a loss of mental capacity, which, however, cannot be detected by conventional neuropsychological tests. These individuals do not inevitably develop dementia. However, it has been shown that they are at an increased risk.
Alzheimer's Disease Antibody Diagnostics Drugs Neurodegenerative Diseases Research Technology Walking
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