A recent study successfully isolated and sequenced century-old RNA molecules from a Tasmanian tiger specimen preserved at room temperature in a museum collection. This achievement marked the first-ever reconstruction of skin and skeletal muscle transcriptomes from an extinct species. The research te
Tasmanian tiger specimen used in the study and preserved in desiccation at room temperature in the Swedish National History Museum in Stockholm.” Credit: Emilio Mármol Sánchez and Panagiotis Kalogeropoulos .molecules from a Tasmanian tiger specimen preserved at room temperature in a museum collection. This achievement marked the first-ever reconstruction of skin and skeletal muscle transcriptomes from an extinct.
“Resurrecting the Tasmanian tiger or the woolly mammoth is not a trivial task, and will require a deep knowledge of both the genome and transcriptome regulation of such renowned species, something that only now is starting to be revealed,” says Emilio Mármol, the lead author of a study recently published in the Genome Research journal by researchers at SciLifeLab in collaboration with the Centre for Palaeogenetics*, a joint venture between the Swedish Museum of Natural History andThe...
This pioneering study opens up new exciting opportunities and implications for exploring the vast collections of specimens and tissues stored at museums across the globe, where RNA molecules might await to be uncovered and sequenced.genomes such as SARS-CoV2 and their evolutionary precursors from the skins of bats and other host organisms held in museum collections”, says Love Dalén, Professor of evolutionary genomics at Stockholm University and the Centre for Palaeogenetics.
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