Researchers at the Leibniz Institute for Immunotherapy (LIT) studied hundreds of patients with acute myeloid leukemia (AML). They discovered that specific mutations in the STAG2 protein cause altered DNA folding in the cell nucleus, thereby contributing to the development of AML.
STAG2 protein mutations and associated spatial alteration of DNA structure can contribute to development of leukemia retrieved 13 August 2024 from https://medicalxpress.com/news/2024-08-stag2-protein-mutations-spatial-dna.html
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