Measurement error may be the culprit in underdiagnosing obstructive sleepapnea in Black patients compared with White patients, based on data.
Measurement error may be the culprit in underdiagnosing obstructive sleep apnea in Black patients compared with White patients, based on data from nearly 2,000 individuals.
"We wanted to examine the implications for obstructive sleep apnea," which is often caused by a reduction in air flow, Azarbarzin said in an interview.presented at the ATS annual meeting, Azarbarzin and colleagues examined data from 1955 adults who were enrolled in the Multi-Ethnic Study of Atherosclerosis Exam 5. The study participants underwent unattended 15-channel polysomnography that included a finger pulse oximeter. The mean age of the participants was 68.3 years and 53.
Severity of obstructive sleep apnea was based on the hypoxic burden, which was defined as the total area under the respiratory curve. The total ventilatory burden was defined as the event-specific area under the ventilation signal and identified by amplitude changes in the nasal pressure signal. The researchers then calculated desaturation sensitivity as hypoxic burden divided by ventilatory burden.
The difference in desaturation sensitivity by race could be caused by differences in physiology or in measurement error, Azarbarzin told. If measurement error is the culprit,"we may be underestimating OSA severity in Blacks," especially in Black women, he said.
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