Study reveals that soft gums are more prone to inflammation tohoku_univ SciReports
concentration in the culture supernatant was quantified using a competitive immune assay with high sensitivity . The assay is based on a competitive reaction to an anti-PGEand the sample. Briefly, the samples or PGEmonoclonal antibody and alkaline phosphatase covalently bound to PGEin a 96-well GxM IgG microtiter plate for 2 h at room temperature on a shaker.
Paxillin expression was measured only at the tip of the cell projection.The cells on the collagen-coated polystyrene culture plate and PDMS were scraped and lysed by ultrasonication in radioimmunoprecipitation assay buffer containing protease and phosphatase inhibitors. Cell lysates were centrifuged at 15,000×for 20 min. The supernatants were mixed with 2-mercaptoethanol and 4 × Laemmli sample buffer and incubated at 95 °C for 5 min.
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Study finds no association between gout and neurodegenerative diseases in the general populationA study published in Scientific Reports highlights that gout can increase the risk of Alzheimer’s disease and Parkinson’s disease in younger or overweight individuals. The study was conducted in a representative Korean population.
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Sensing Psychological Well-being Using Social Media Language: Prediction Model Development StudyBackground: Positive mental health is arguably increasingly important and can be revealed, to some extent, in terms of psychological well-being (PWB). However, PWB is difficult to assess in real time on a large scale. The popularity and proliferation of social media make it possible to sense and monitor online users’ PWB in a nonintrusive way, and the objective of this study is to test the effectiveness of using social media language expression as a predictor of PWB. Objective: This study aims to investigate the predictive power of social media corresponding to ground truth well-being data in a psychological way. Methods: We recruited 1427 participants. Their well-being was evaluated using 6 dimensions of PWB. Their posts on social media were collected, and 6 psychological lexicons were used to extract linguistic features. A multiobjective prediction model was then built with the extracted linguistic features as input and PWB as the output. Further, the validity of the prediction model was confirmed by evaluating the model's discriminant validity, convergent validity, and criterion validity. The reliability of the model was also confirmed by evaluating the split-half reliability. Results: The correlation coefficients between the predicted PWB scores of social media users and the actual scores obtained using the linguistic prediction model of this study were between 0.49 and 0.54 (P<.001), which means that the model had good criterion validity. In terms of the model’s structural validity, it exhibited excellent convergent validity but less than satisfactory discriminant validity. The results also suggested that our model had good split-half reliability levels for every dimension (ranging from 0.65 to 0.85; P<.001). Conclusions: By confirming the availability and stability of the linguistic prediction model, this study verified the predictability of social media corresponding to ground truth well-being data from the perspective of PWB. Our study has positive imp
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Hangover jab that could 'reverse drunkenness' tested by scientists in new studyAcademics hope the finding will lead to effective treatments for alcohol poisoning, which can have serious health effects on the body.
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Joe Mixon: Child injured amid reports of gunshots at home of Cincinnati Bengals NFL starA child was taken to hospital after a shooting at the home of NFL star Joe Mixon. Police searched the house and have launched an investigation.
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World's most comprehensive study on COVID-19 mental health finds limited effects for most peopleCOVID-19 has taken a relatively limited toll on the mental health of most people around the globe, according to a paper published today in The BMJ by a McGill University-led research team involving collaborators from McMaster University, the University of Toronto, and other institutions.
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Mental-health crisis from pandemic was minimal - studyMost people remained resilient, BMJ research suggests, but others say some groups were badly affected.
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